The HIV-1 gp120, Strain IIIB (Human Immunodeficiency Virus Type 1) Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to HIV gp120, and HIV-1 (Human Immunodeficiency Virus Type 1). The HIV-1 gp120, Strain IIIB (Human Immunodeficiency Virus Type 1) Antibody has been validated for the following applications: Block/Neutralize/Inhibit, ELISA, Immunohistochemistry, Immunoprecipitation, and Western Blot.
Description
HIV-1 is equipped with the envelope gp160 glycoprotein for interaction with Langerhans cells (LCs) and dendritic cells (DCs), the members of the innate immune system, which confront the virus at the portal of virus entry in the human body. These cells are equipped with receptors by which they bind and endocytose the virus. The gp120 glycoprotein is used for binding to CD4 receptor and CCR5 co-receptor of T helper 2 (Th2) cells, and is able to induce FcepsilonRI(+) hematopoietic cells to produce IL4, which inactivates the host adaptive immune response